Products

The products manufactured at S.M. Farmaceutici S.r.l. include large and small volume solutions for Infusion, Solutions for Peritoneal Dialysis, for Haemofiltration and Haemodiafiltration, Contrast Media, solutions for Veterinary use and Medical devices including Concentrated Solutions for Haemodialysis, Priming and Irrigation solutions, Sterile Solutions for Continuous Renal Replacement Therapy.

Thanks to our high production technology, high quality standard and process flexibility, we can offer to our Customers qualified services from the
production formulation phase to the industrialization of products, including validations of production process and analytical methods.

The annual production capacity is of 40 million unities in glass bottles and 4 million liters of solutions in bags.

Products manufactured at Manufacturing plant in Potenza are included in three main lines:

Bottles Line

Pharmaceutical Products:

  • Standard Solutions
  • Aminoacid Solutions
  • Plasma Expanders
  • Anaesthetic Solutions
  • Metronidazole
  • Paracetamol
  • Contrast Media

Bags Line

Pharmaceutical Products:

  • Haemofiltration Solutions
  • Haemodiafiltration Solutions
  • Aminoacid Solutions
  • Standard Solutions

Medical Devices:

  • Irrigation Solutions
  • Haemodialysis Solutions
  • Haemofiltration Solutions
  • Haemodiafiltration Solutions
  • Solutions for Continuous Renal Replacement Therapy

Corticosteroid solutions

Pharmaceutical Products:

  • Betamethason Sodium Phosphate 5mg/100ml
The products dispensed in glass containers are processed with a completely automated line with a capacity of 9000 pieces per hour. The line is equipped with filling–stoppering–capping machine of new generation, two superheated water autoclaves for sterilization and an electronic machine for final inspection of the finished product.Thanks to the high flexibility of the line a wide range of primary containers and closure systems can be used :
Product Volume Neck
Sterile product in glass
50 ml
100 ml
250 ml
500 ml
20 mm
29 mm
32 mm
Water for Injection
Sodium Chloride 0,9%
Glucose 5%,10%,20%,33%,50%
Mannitol 5%,10%,18%

Ringer Acetate
Ringer Lactate
Electrolytes Solutions

AAcids Solutions
Metronidazole 0,5gr/100 ml
Paracetamol 1gr/100 ml
Contrast Media
The products dispensed in flexible containers are processed on a partially automated line with a filling capacity of 2.000 liters per hour, equipped with an air-steam autoclave for sterilization. Thanks to the high flexibility, a large range of primary containers and closure systems can be used, like PVC and PP, with or without overwrap, one or two tubes, from 50 ml to 5000 ml.
Product Material Volume
Sterile product in bag
PP
PVC
50 ml 100 ml
500 ml
1000 ml
2000 ml
5000 ml
Water for Injection
Sodium Chloride 0,9%

Glucose 5%
Priming Solutions
Haemofiltration Solutions
Haemodiafiltration Solutions
Citrate Solutions
AAcids Solutions
Potassium Correctors
The production of Corticosteroid solutions is carried out in a dedicated area , all activities like preparation of solutions, filtration and filling are performed in rooms class C with an HVAC system used exclusively for this area. The access to this area is subject to very restrictive procedure and the personnel attendant is constantly trained. The high flexibility of filling machine make possible to produce the Corticosteroid solutions in a large range of primary containers with many different closure systems.
Product Material Volume
Corticosteroid solutions in bags PP
PVC
100 ml
500 ml
1000 ml
2000 ml
5000 ml
Betamethasondihydrogenphosphat-dinatrium 5mg/100ml